Mamoru Yamaguchi


Professor Emeritus

Contact Goss Laboratory
1925 Coffey Road
Columbus, OH 43210
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Veterinary Biosciences

Professional Training and experience

  • BS (Meat Science), 1966, Obihiro University, Obihiro, Japan
  • MS (Muscle Biochemistry), 1968, Hokkaido University, Sapporo, Japan
  • PhD (Muscle Biology), 1972, University of Wisconsin, Madison, Wisconsin

Research Interests

  • Muscle structure, muscle contraction
  • Muscle diseases, skeletal and cardiac muscle
  • Cardiovascular system
  • Muscle protein isolation, characterization
  • Immunomolecular biology: CD antigens, cytokines, dendritic cells
  • Electrophysiology: EC coupling
  • Electron microscopy
  • Atomic force microscopy

Professional Service

  • Scientific journal referee
    • Journal of Molecular Biology
    • Journal of Cell Biology
    • Journal of Muscle Research and Cell Motility
    • American Journal of Veterinary Research
    • Food Microstructure
    • Bone
    • Acta Anatomica
    • Journal of Rheumatology
    • Biotechniques

Administrative Service

  • Rakuno Gakuen University visiting scholar coordinator

Professional Organizations

  • Society of Sigma XI, 1971 to present
  • Biophysical Society, 1974 to present
  • American Heart Association (Ohio Chapter), 1978 to present
  • American Heart Association (National) Committee Basic Sciences, 1980 to present
  • American Society for Cell Biology, 1982 to present
  • American Meat Science Association, 1992 to present
  • The Ohio Academy of Science, 1995 to present


Yu-Chieh Wang, Samuel K. Kulp, Chih-Cheng Yang, Aaron M. Sargeant, Ya-Ting Yang, Mamoru Yamaguchi, Yoko Kashida, Geen-Dong Chang, and Ching-Shih Chen.  Combination of celecoxib derivative OSU03012 and EGFR inhibitors enhances cell death in gefitinib/erlotinib-resistant lung cancer cells through induction of ER stress-related apoptosis and suppression of Akt signaling.  Cancer Res.(2008)  68(8): 2820-2830

Niu,N, Y. M. Yamaguchi and Rikihisa, Subversion of cellular autophagy by Anaplasma phagocytophilum. Cellular Microbiology 10(3):593-605 (2008)

Sargeant A, Klein R, Rengel R, Clinton S, Kulp S, Kashida Y, Yamaguchi M, and Chen CS.  Chemotherapeutic and bioenergetic signaling effects of PDK1/Akt pathway inhibition in a transgenic mouse model of prostate cancer.  Toxicol Pathol 35(4):549-61 (2007)

Zimmerman, B., M. Yamaguchi and L. Rush Immunoglobulin Crystals in Reactive Plasma Cells in a Dog. Veterinary Pathology 44:389-391 (2007)

Muto M, Sargeant A, Tangkawattana P, Nishijima Y, Bonagura J, Hoshijima M, Nakade T, Hosaka Y, Faulkner G, Yamaguchi M. Intranuclear paracrystals observed in Striated Muscle Specific LIM Protein (MLP-/-) mouse cardiomyocytes.  Microsc Res Tech 70(1):50-54 (2007) 

Wuthichai Klomkleaw, Prasarn Tangkawattana, Tsonwin Hai, Yoshichika Okamoto, Makoto Muto and Mamoru Yamaguchi   ATF3 Transgenic Mice: Structural Analysis of Cardiac Myocytes. Science Asia 33:265-271 (2007) 

Groff, B. A. Munoz-Garcia,  M. Yamaguchi,  J.B. Williams. Development of skin structure and cutaneous water loss in nestling desert House sparrows from Saudi Arabia. Comparative Biochemistry and Physiology Part A 147(2):493-501 (2007)