People

Rustin Moore

DVM, PhD Diplomate ACVS

Dean, College of Veterinary Medicine; Ruth Stanton Chair in Veterinary Medicine

Contact

moore.66@osu.edu (614) 688-8749/(614) 292-2363 Veterinary Medicine Academic Building
1900 Coffey Road
Columbus, OH 43210
Map Link

Department

Veterinary Clinical Sciences

Professional Training and experience

  • BS, West Virginia University, 1986
  • DVM, OSU, 1989
  • PhD, OSU, 1994
  • Assistant Professor, Louisiana State University, 1994
  • Associate Professor, Louisiana State University, 1997
  • Professor, Louisiana State University, 2000

Research Interests

  • Pathophysiology of acute laminitis in horses
  • Equine gastrointestinal physiology, pharmacology and pathophysiology
  • Equine gastrointestinal surgery and its associated complications
  • Equine vascular and nonvascular smooth muscle physiology and pharmacology
  • Pathophysiology and mediators of endotoxemia and shock\

Research Summary

  • Understanding the pathophysiology of acute laminitis in horses and the subsequent development of effective therapeutic and preventive strategies.
  • Understanding the physiology, pharmacology and pathophysiology of vascular and nonvascular smooth muscle pertaining to laminitis and gastrointestinal and respiratory tract disease in horses leading to the discovery of novel and effective preventative and therapeutic strategies for horses with laminitis, colic and heaves.
  • Understanding the pathophysiology of gastrointestinal disease (colic) in horses, including ischemia, ischemia-reperfusion injury and endotoxemia and identifying more effective treatments.

Select Honors and Awards

  • West Virginia University Academy of Distinguished Alumni, 2015
  • National Gamma Award, Omega Tau Sigma Fraternity, 2012
  • Commencement Speaker, Davis College of Agriculture, Natural Resources and Design, West Virginia, 2010 University
  • Lifetime Achievement Award, Fifth International Equine Conference on Laminitis and Diseases of the Foot, 2009
  • Bud and Marilyn Jenne Professorship in Equine Medicine, College of Veterinary Medicine, The Ohio State University, 2008 to present
  • Marty Simensen Memorial Trophy, Dressage at Devon, 2006
  • Paula and Milton W. Shepard Professorship in Veterinary Medicine, School of Veterinary Medicine, Louisiana State University, October 2004
  • Faculty Distinguished Scholar Award, School of Veterinary Medicine, Louisiana State University, 2002
  • LSU Distinguished Faculty Award, Louisiana State University, 2001
  • Greater Baton Rouge Area Forty Under 40, Baton Rouge Business Report, 1997
  • Young Distinguished Alumni Award, West Virginia University College of Agriculture and Forestry Alumni Association, 1997
  • Pfizer Animal Health Award for Research Excellence, School of Veterinary Medicine, Louisiana State University, 1996

Select Professional Memberships and Service

  • American Veterinary Medical Association, Member, 1989 to present
  • American College of Veterinary Surgeons, Member, 1994 to present
  • American Association of Equine Practitioners, Member, 1994 to present
    • Member, AAEP on Call Team, 2008 to present
    • Equine Research Coordination Group Committee, Member, 2003 to present
    • AAEP Foundation Past Presidents’ Fellow Scholarship Subcommittee, Member, 2006 to 2014
    • AAEP Foundation Advisory Committee, 2006-2012
    • AAEP State Equine Emergency Network, Liaison, 2006 to 2009
    • Board of Directors, At Large Member, 2006 to 2009
    • AAEP Foundation Research Subcommittee, Member, 2005 to 2009
    • Education Task Force Organizer, Chair and Moderator of Education Summit, Cincinnati, OH, 2007
    • Educational Programs Committee, Member, 2004 to 2007
    • State Equine Emergency Network, Liaison, 2006 to 2009
    • Educational Programs Committee, Member, 2004 to 2007
    • Research Committee, Member (1997 to 2002) and Chair (2000 to 2002)
  • American Association of Veterinary Clinicians (AAVC)
    • Member, 1994 to present
    • Executive Committee, 2010 to 2013
    • Immediate Past President, 2012 to 2013
    • President, 2011 to 2012
    • President Elect, 2010 to 2011
  • American College of Veterinary Surgeons (ACVS)
    • Liaison to Public Outreach Committee, October 2010 to 2013
      • Large Animal Liaison to Resident Credentialing Committee, October 2010 to 2013
      • Website Redesign Working Group, October 2010 to 2013
    • Examination Committee, July 2000-February 2004
      • Examiner for Oral Exam for the European College of Veterinary Surgeons, 2004
    • Publications Committee, Member, January 1995 to December 1997
      • Chair, January 1997 to December 1997
  • Grayson-Jockey Club Research Foundation, Inc. - Research Advisory Committee, Member, 1998 to 2000
  • USA Equestrian, Inc. - Scientific Review Panel - Research Committee, Member, 2000 to 2003
  • Louisiana Veterinary Medical Association (LVMA)
    • LVMA Equine Committee
      • District 9 Representative - 2000 to 2006
      • Equine Committee Foundation - Member & President, 2005 to 2006

Leadership and Administrative Service

  • Alice Lloyd Finley Memorial Research Farm, College of Veterinary Medicine, The Ohio State University, July 2014 to present
  • College of Veterinary Medicine, The Ohio State University, Associate Executive Dean, 2014 to present
  • Veterinary Medical Center, College of Veterinary Medicine, The Ohio State University, Acting Director, 2009 to 2011, and Executive Director, 2011 to present
  • College of Veterinary Medicine, The Ohio State University, Associate Dean of Clinical and Outreach Programs, 2011 to 2014
  • Department of Veterinary Clinical Sciences, College of Veterinary Medicine, The Ohio State University, 2006 to 2014
  • Equine Health Studies Program, School of Veterinary Medicine, Louisiana State University - Director, 2000 to 2006
  • Veterinary Teaching Hospital & Clinics, School of Veterinary Medicine, Louisiana State University - Service Chief, Equine Medicine and Surgery, 2000 to 2006

Graduate Student, Resident and Intern Mentoring

  • 9 Thesis (MS) Student Committees - 5 major or co-major professor
  • 12 Doctoral (PhD) Student Committees - 7 major or co-major professor
  • Advisor/Mentor for 16 Residents and 24 Interns

Publications

(Selected from over 120 peer- and editor-reviewed scientific articles)

  • Fugler LA, Eades SC, Moore RM, Koch CE, Keowen ML: Plasma matrix metalloproteinase activity in horses after intravenous infusion of lipopolysaccharide and treatment with matrix metalloproteinase inhibitors. Am J Vet Res 74 (3) 473-480, 2013.
  • Wong DM, Moore RM, Brockus C: Intestinal ischemia-reperfusion injury in horses: Pathogenesis and therapeutics. Compend Contin Educ Pract Vet 34 (8) E1-E7, 2012.
  • Wong DM, Moore RM, Brockus DW: Mechanisms of oxidative injury in equine disease. Compend Contin Educ Pract Vet 34 (8) E1-E8, 2012.
  • Venugopal CS, Mendes LCN, Peiro JR, Laborde SS, Stokes AM, Moore RM: Transcriptional changes associated with recurrent airway obstruction in affected and unaffected horses. Am J Vet Res 71 (4) 476-482, 2010.
  • Costa LRR, Eades SC, Venugopal CS, Moore RM: Plasma and pulmonary fluid endothelin in horses with seasonal recurrent airway obstruction. J Vet Intern Med 23 (6) 1239-46, 2009.
  • Hanly BK, Stokes AM, Bell AM, Johnson JR, Keowen ML, Paulsen DB, Sod GA, Moore RM: Use of serial laminar tissue collection via biopsy in conscious healthy horses. Am J Vet Res 70 (6):697-702, 2009.
  • Rosol TJ, Moore RM, Saville WJA, Oglesbee MJ, Rush LJ, Mathes LE, Lairmore MD: The need for veterinarians in biomedical research. J Vet Med Educ 36 (1) 70-75, 2009.
  • Venugopal CS, Holmes EP, Polikepahad S, Laborde S, Kearney M, Moore RM: Neurokinin receptors in recurrent airway obstruction: A comparative study of affected and unaffected horses. Can J Vet Res 73 (1):25-33, 2009.
  • Mendes HMF, Faleiros RR, Vasconcelos AC, Alves GES, Moore RM: Apoptose no cólon menor eqüino submetido à isquemia e reperfusão experimentais. Pesq Vet Bras 29 (3) 198-204, 2009.
  • Rotting AK, Freeman DE, Constable PD, Moore RM, Eurell JC, Wallig MA, Hubert JD: The effects of Strongylus vulgaris parasitism on eosinophil distribution and accumulation in equine large intestinal mucosa. Equine Vet J 40 (4) 379-384, 2008.
  • Vidal MA, Robinson SO, Lopez MJ, Paulsen DB, Borkhsenious O, Johnson JR, Moore RM, Gimble JM: Comparison of chrondrogenic potential in equine mesenchymal stromal cells derived from adipose tissue and bone marrow. Vet Surg 37 (8) 713-724, 2008.
  • McConnico RS, Morgan TW, Williams CC, Hubert JD, Moore RM: Pathophysiologic effects of phenylbutazone on the right dorsal colon in horses. Am J Vet Res 69 (11) 1-11, 2008.
  • Polikepahad S, Haque M, Francis J, Moore RM, Venugopal CS: Characterization of endothelin receptors in the peripheral lung tissues of horses unaffected and affected with recurrent airway obstruction. Can J Vet Res 72 (4) 340-349, 2008.
  • da Cunha AF, Stokes AM, Chirgwin S, Pettifer G, Moore RM: Quantitative expression of the TRPV-1 gene in central and peripheral nervous tissues in horses. Intern J Appl Res Vet Med 6 (1) 15-23, 2008.
  • Moore RM: Evidence-based treatment of laminitis-What works? J Equine Vet Sci 28 (3) 176-179, 2008.
  • Faleiros RR, Macoris DG, Alves GE, Souza DG, Teixeira MM, Moore RM: Local and remote lesions in horses subjected to small colon distension and decompression. Can J Vet Res 72 (1) 68-76, 2008.
  • Hubbell JAE, Saville WJA, Moore RM: Frequency of activities and procedures performed in private equine practice and proficiency expected of new veterinary school graduates. J Am Vet Med Assoc 232 (1) 42-46, 2008.
  • Leise BS, Fugler LA, Stokes AM, Eades SC, Moore RM: Effects of intramuscular administration of acepromazine on palmar digital blood flow, palmar digital arterial pressure, transverse facial artery pressure, and packed cell volume in clinically healthy, conscious horses. Vet Surg 36 (8) 717-723, 2007.
  • Vidal MA, Kilroy GE, Johnson JR, Lopez MJ, Moore RM; Gimble JM: Characterization of equine adipose tissue-derived stromal sells: Adipogenic and osteogenic capacity and comparison with bone marrow-derived mesenchymal cells. Vet Surg 36 (7) 613-622, 2007.
  • McConnico RS, French DD, Clark B, Mortensen KE, Littlefield M, Moore RM: Equine rescue and response activities in Louisiana in the aftermath of Hurricanes Katrina and Rita. J Am Vet Med Assoc 231 (3) 384-392, 2007.
  • Polikepahad S, Moore RM, Venugopal CS: Endothelins and airways – A short review. Res Comm Mol Path Pharm 119, 3-51, 2006.
  • Eades SC, Stokes AM, Johnson PJ, LeBlanc CJ, Ganjam VK, Buff PR, Moore RM: Serial alterations in digital hemodynamics and endothelin-1 immunoreactivity, platelet-neutrophil aggregation, and concentrations of nitric oxide, insulin and glucose in blood obtained from horses following carbohydrate overload. Am J Vet Res 68 (1) 87-94, 2007.
  • Vidal MA, Kilroy GE, Johnson JR, Lopez MJ, Moore RM, Gimble JM: Cell growth characteristics and differentiation frequency of adherent equine bone marrow–derived mesenchymal stromal cells: Adipogenic and osteogenic capacity. Vet Surg 35, 601-610-2006.
  • Stokes AM, Venugopal CS, Hosgood G, Eades SC, Moore RM: Comparison of 2 endothelin-receptor antagonists on in vitro responses of equine palmar digital arterial and venous rings to endothelin-1. Can J Vet Res 70 (3)197-205, 2006.
  • Eades SC, Stokes AM, Moore RM: Effects of an endothelin receptor antagonist and nitroglycerin on digital vascular function in horses during the prodromal stages of carbohydrate overload-induced laminitis. Am J Vet Res 67 (7) 1204-1211, 2006.
  • Hubert JD, Burba DJ, Moore RM: Evaluation of a vessel-sealing device for laparoscopic granulose cell tumor removal in standing mares. Vet Surg 35 (4) 324-329, 2006.
  • Venugopal CS, Polikepahad S, Holmes EP, Heuvel JV, Leas TL, Moore RM: Endothelin receptor alterations in equine airway hyperreactivity. Can J Vet Res 70 (1) 50-7, 2006.
  • Polikepahad S, Paulsen DB, Moore RM, Costa LRR, Venugopal CS: Immunohistochemical determination of expression of endothelin receptors in bronchial smooth muscle and epithelium of healthy horses and horses affected by summer pasture-associated obstructive pulmonary disease. Am J Vet Res 67 (2) 348-357, 2006.
  • Gilhooly M, Eades SC, Stokes AM, Moore RM: Effects of topical nitroglycerine patches and nitroglycerine ointment on digital venous plasma nitric oxide concentrations and digital blood flow in healthy conscious horses. Vet Surg 34, 604-609, 2005.
  • Chidambaram RM, Eades SC, Moore RM, Hosgood GL, Venugopal CS: Characterization of in the in vitro responses of equine cecal longitudinal smooth muscle to endothelin-1. Am J Vet Res 66 (7) 1202-1208, 2005.
  • Mirza MH, Seahorn TL, Oliver JL, Hosgood G, Moore RM: Detection and comparison of nitric oxide in clinically healthy horses and those with naturally acquired strangulating large colon volvulus. Can J Vet Res 69 (2) 106-115, 2005.
  • McConnico RS, Stokes AM, Eades SC, Moore RM: Investigation of the effect of black walnut extract on in vitro ion transport and structure of equine colonic mucosa. Am J Vet Res 66 (3) 443-449, 2005.