Protein in the urine (proteinuria) is common in dogs and causes further damage to the kidneys. This study aims to determine whether the standard drugs used to treat proteinuria can completely suppress one of the hormones involved in kidney regulation, and whether lack of complete suppression affects the amount of proteinuria.
Syringomyelia (SM) is a painful neurological problem which causes neuropathic pain (NP) behaviors such as scratching, face rubbing, and intermittent vocalizations in affected dogs. Pain management of SM-NP is currently limited by the lack of objective ways to assess severity of pain in dogs with the condition. The long-term goal of our group is to improve the diagnosis and management of neuropathic pain in dogs.
The results of this research should allow us to determine whether the new antigen receptor gene annotation and new computational techniques we have developed are suitable to accurately identify clonal expansions of lymphocytes in dogs with naturally occurring lymphoma and leukemia.