Correlation of plasma levels of a potential biomarker (CK-18) with diarrhea in dogs with mast cell tumor treated receiving toceranib (Palladia). -- The purpose of this pilot study is to determine if plasma CK18 levels can be used as a biomarker that can predict GI side effects in dogs receiving toceranib.
Evaluation of Allergenic Extract Intradermal Threshold Concentration Variation in Non-Allergic Dogs. -- The purpose of this study is to establish threshold concentrations of allergens by a new veterinary allergen company.
Phase I safety study of STA-12-8960 in dogs with spontaneous tumors; comparison with irinotecan. -- The objective of this study is to compare the plasma and intratumoral concentrations of SN-38, the active metabolite of irinotecan, in dogs with soft tissue sarcoma receiving first irinotecan followed by STA-12-8960 to determine whether STA-12-8960 does result in greater intratumoral drug concentrations.