CHASE Questionnaire* to Assess the Safety and Efficacy of a Novel Pain Management Product in Dogs

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Purpose and brief explanation of the study

The goals of this study are to evaluate a newly developed questionnaire to assess pain and clinical signs associated with CM/SM in dogs and to evaluate how well a novel veterinary pain management product might treat the condition.


What qualifies my pet for enrollment?

•             Generally healthy Cavalier King Charles Spaniels (6 months- 8 years of age)

•             Displaying signs of CM/SMPicture of a Cavalier King Charles Spaniel

•             Able to wear a harness

•             Not receiving gabapentin or pregabalin in the 7 days prior to study enrollment

•             Able to undergo anesthesia for MRI diagnosis of their condition


What does enrolling my pet in this clinical trial involve?

Dogs with signs of CM/SM dogs will visit the VMC for an initial screening visit to assess their overall health and clinical signs and to perform testing to confirm that they have CM/SM. They will be enrolled in the study for a total of about a month and will need to visit the veterinary medical center two additional times, at about 2 weeks and 4 weeks after enrolling. At the start of the study, your dog will be randomized to receive either the study drug, or a placebo for 2 weeks. After 2 weeks, your pet will be assigned to the alternate group.  You will be provided rescue pain medications that you can use in case your dog requires additional pain management at home during the study. You will be asked to complete a survey at four time points to assess your dog’s clinical signs associated with CM/SM, will need to maintain a diary to capture any abnormal signs or behaviors while your dog is on the study, and will be asked to maintain a record of each time you administer medications to your dog.

Client compensation

Enrollment in this study group requires your dog to have an MRI documenting CM/SM within the last 90 days. The study will cover the cost of this, and the other prescreening requirements, if your dog appears otherwise eligible for the study. The cost of all study-related visits and study-related medications is covered by the study.


Dr. Sarah Moore


*Copyright TriviumVet 2022