Cryoprecipitate is rich in factor VIII and von Willebrand's factor, so it is used for the treatment of hemophilia A and von Willebrand's disease; it can also be used as a topical hemostatic in surgery.

Protocol for use of cryoprecipitate

  • Cryoprecipitate should be thawed in a 37°C water bath in a waterproof plastic bag. Do not thaw in the refrigerator!
  • Cryoprecipitate must be administered with a standard in-line blood filter.
  • The dose is 1 unit/10 kg.
  • The dose can be repeated every 12 hours.