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Cryoprecipitate-poor Plasma contains all coagulation factors except von Willebrand's factor and factor VIII. Therefore, it can be used in the treatment of rodenticide toxicity as well as the replacement of proteins (albumin and immunoglobulins). Cryopoor Plasma SHOULD NOT be used to treat von Willebrand's disease or Hemophilia A.
Protocol for use of Cryopoor Plasma
- Cryopoor Plasma should be thawed in a 37°C water bath in a waterproof plastic bag. Do not thaw in the refrigerator!
- Cryopoor Plasma must be administered with a standard in-line blood filter.
- The dose is 6-12 ml/kg, but in severe deficit of coagulation factors or immunoglobulin, you can use up to 20 ml/kg. This should be given over 2-4 hours.