Dr. Daria J. Hazuda received her Ph.D. in biochemistry from the State University of New York, Stony Brook, where she trained with Dr. Cheng-Wen Wu. She performed her postdoctoral studies at Smith, Kline, and French in their Department of Molecular Genetics. In 1989, Dr. Hazuda joined Merck Research Laboratories as a Senior Research Biochemist and is now Vice President and Therapeutic Area Head, Infectious Diseases, and Chief Scientific Officer of the Merck Exploratory Science Center.
While at Merck Research Laboratories, Dr. Hazuda has focused on the development of antiviral therapeutics. Her leadership led to the development of the first HIV-1 integrase inhibitor Isentress (Raltegravir) as well as HCV inhibitors Elbasvir and Grazoprevir. In addition to her work in drug development, Dr. Hazuda made seminal contributions to our understanding of the HIV-1 integrase mechanism, including the roles of divalent cations in integration complex assembly and enzymatic activity. In 2008, her group performed one of three landmark genome scale siRNA screens to identify host factors that influence HIV-1 infection.
Dr. Hazuda is an author of over 190 research articles, reviews and book chapters. She holds 28 U.S. patents. She serves on the amfAR, American Foundation for AIDS Research, Advisory Council and the editorial boards of ACS Infectious Diseases and the Journal of Virus Eradication. She has previously served on NIH study sections and the HCV Drug Resistance Advisory Group.
In 2010 Dr. Hazuda was elected as a Fellow to the American Academy of Microbiology. She has been awarded several international honors, including the David Barry DART Development of Antiretroviral Therapies Achievement Award and the Italian Premio Galeno Award for her work with Isentress.
Dr. Hazuda was selected by the Center for Retrovirus Research of The Ohio State University to receive the 2018 Distinguished Research Career Award in recognition of her substantial body of work on retroviruses and antiviral therapeutics.
Dr. Daria Hazuda receives Career Award crystal from Center for Retrovirus Research member Kristine Yoder (right).
Dr. Daria Hazuda during her distinguished research seminar presentation to the Center for Retrovirus Research and OSU faculty, staff, and students.
Dr. Daria Hazuda with CRR members. Shown from left are (kneeling) Jesse Kwiek, Sanggu Kim, (standing) Michael Oglesbee, Karin Musier-Forsyth, Lawrence Mathis, Patrick Green, Daria Hazuda, Ross Larue, Kristine Yoder, Li Wu, Namal Liyanage