The 2002 Distinguished Research Career Awardee is Dr. Hung Fan of the University of California, Irvine. Dr. Fan is Professor of Virology, Department of Molecular Biology and Biochemistry, Director of the Cancer Research Institute, and Co-Director of the Chao Family Comprehensive Cancer Center. In addition to his academic appointments, Dr. Fan is Editor, Journal of Virology, is a member of the editorial boards of Virus Genes and the Journal of Biomedical Science, and is Chair of the NIH Virology Study Section. He also serves on a number of important scientific advisory committees at the local, national, and international levels.
Dr. Fan has used multiple retroviral systems (Moloney murine leukemia virus, human T-lymphotropic virus, and simian and human immunodeficiency viruses) to make important contributions to understanding the regulation of eucaryotic gene expression, chromatin structure, and the pathogenesis of AIDS. Dr. Fan has made key contributions to understanding carcinogenesis by Jaagsiekte sheep retrovirus, which is a virally induced non-smoking-related bronchioalveolar carcinoma. His findings include the groundbreaking discovery that Jaagsiekte virus envelope protein induces cellular transformation, which has opened the door to new understanding of human lung cancer. Dr. Fan continues to elucidate how the envelope protein causes cancer in sheep and will ultimately develop treatment and/or prevention strategies against this pervasive human cancer.
Dr. Fan spent two days at The Ohio State University presenting two seminars on his research and meeting with faculty, postdoctoral fellows, and graduate students.
The 2002 Distinguished Research Career award was sponsored by the Center for Retrovirus Research, the Comprehensive Cancer Center, the Interdisciplinary Biomedical Sciences Graduate Program, and the James Cancer Hospital and Solove Research Institute.