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Platelet Therapy Can Provide Relief for Dogs with Osteoarthritis

Dr. Alicia L. Bertone, professor and Director of the Comparative Orthopedic Research Laboratory at The Ohio State University College of Veterinary Medicine co-authored a new study that shows evidence that platelet therapy can provide relief for dogs with osteoarthritis.

"This study is the first to provide evidence in support of platelet therapy for canine osteoarthritis,” said Dr. Alicia L. Bertone, senior author of the study.

Osteoarthritis is a progressive chronic degenerative joint disease characterized by pain and stiffness in the joints. Patients are typically treated with pain killers, weight loss plans, and exercise. However, this new study shows evidence that canine platelet enhancement therapy (C-PET) can improve a patient’s health and decrease its pain.

C-PET from MWI is a filter-based system that relies on Pall’s unique technology to concentrate platelets and their associated growth factors – which enhance wound healing and induce tissue regeneration – from a small volume of a dog’s own blood.

During the study, 20 client-owned dogs volunteered to participate (10 at Ohio State and 10 at Western University). All dogs were randomized to receive either saline or platelet therapy produced with the C-PET product. They were evaluated prior to treatment and again three months after treatment. At the end of the three month period owners of dogs who received saline were given the option to cross over to C-PET treatment and be re-evaluated again three months later.

Study results demonstrated that, on average, animals given C-PET but not saline alone, showed statistically significant improvement in measures of pain and lameness whether using questionnaires or force plate kinetics measurements. Saline treated animals showed no improvements and there was an indication that some may have gotten worse. When those dogs crossed over to the treatment arm, they too improved significantly by all measurement instruments.

To read more about the study, click here.


About the College of Veterinary Medicine at Ohio State

Founded in 1885, The Ohio State University College of Veterinary Medicine is ranked fifth in the nation and includes more than 1,000 faculty, staff and students in the Departments of Veterinary Biosciences, Veterinary Clinical Sciences, and Veterinary Preventive Medicine. The Veterinary Medical Center is one of the largest specialty referral centers in the world, with more than 35,000 farm, equine, and companion animal patients each year. A nationally-recognized ambulatory practice and teaching unit in Marysville, Ohio provides farm animal experience to every veterinary student, and the Food Animal Health Research Program in Wooster, OH focuses on detection, control, and prevention of disease. Located on the only campus in the country with a comprehensive medical center offering seven health sciences colleges, we admit up to 162 veterinary students per class, and offer a new comprehensive graduate program in Veterinary and Comparative Medicine as well as a unique Master’s degree in Veterinary Public Health, in partnership with the College of Public Health.   


Last updated: 

Friday, May 4, 2012 - 2:20pm