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Publications

  1. Nahabedian J, Sharma A, Kaczmarek ME, Wilkerson GK, Sawyer SL, Overbaugh J. Owl monkey CCR5 reveals synergism between CD4 and CCR5 in HIV-1 entry. Virology 2017. 512:180-186. PMID: 28972927.
  2. Feng L, Dharmarajan V, Serrao E, Hoyte A, Larue RC, Slaughter A, Sharma A, Plumb MR, Kessl JJ, Fuchs JR, Bushman FD, Engelman AN, Griffin PR, Kvaratskhelia M. The Competitive Interplay between Allosteric HIV-1 Integrase Inhibitor BI/D and LEDGF/p75 during the Early Stage of HIV-1 Replication Adversely Affects Inhibitor Potency. ACS Chemical Biology 2016. 11(5):1313-21. PMID: 26910179.
  3. Kessl JJ, Sharma A, Kvaratskhelia M. Methods for the analyses of inhibitor-induced aberrant multimerization of HIV-1 integrase. Methods in Molecular Biology HIV Protocols 3rd Edition 2016. 1354:149-64. PMID: 2671471. Book Chapter, ISBN: 978-1-4939-3046-3.
  4. Boyd DF, Sharma A, Humes D, Cheng-Mayer C, Overbaugh J. Adapting SHIVs In Vivo Selects for Envelope-Mediated Interferon-α Resistance. Public Library of Science (PLOS) Pathogens 2016. 12(7):e1005727. PMID: 27399306.
  5. Sharma A, Boyd D, Overbaugh J. Development of SHIVs with circulating, transmitted HIV-1 variants. Journal of Medical Primatology 2015. 44(5):296-300. PMID: 26101933.
  6. *Ronen K, *Sharma A, *Overbaugh J. HIV Transmission Biology: Translation for HIV Prevention. AIDS 2015. 29(17):2219-27. *Equal contributions. PMCID: PMC4640979.
  7. *Meyerson N, *Sharma A, Wilkerson G, Overbaugh J, Sawyer S. Identification of a nonhuman primate CD4 receptor in Spix Owl monkeys broadly compatible with early-stage HIV-1 isolates. Journal of Virology 2015. 89(16):8611-22. *Co-first authors. PMCID: PMC4524261. Featured as cover article.
  8. Sharma A, Slaughter A, Jena N, Feng L, Kessl JJ, Fadel HJ, Malani N, Male F, Wu L, Poeschla E, Bushman FD, Fuchs JR, Kvaratskhelia M. A New Class of Multimerization Selective Inhibitors of HIV-1 Integrase. PLOS Pathogens 2014. 10(5):e1004171. PMCID: PMC4038613.
  9. Aiyer SS, Swapna GV, Malani N, Aramini JM, Schneider WM, Plumb MR, Ghanem M, Larue RC, Sharma A, Studamire B, Kvaratskhelia M, Bushman FD, Montelione GT, Roth MJ. Altering murine leukemia virus integration through disruption of the integrase and BET protein family interaction. Nucleic Acids Research 2014. 42(9):5917-28. PMCID: PMC4027182.
  10. Larue RC, Plumb  MR, Crowe BL, Shkriabai N, Sharma A, Difiore J, Malani N, Aiyer SS, Roth MJ, Bushman FD, Foster MP, Kvaratskhelia M. Bimodal high-affinity association of Brd4 with murine leukemia virus integrase and mononucleosomes. Nucleic Acids Research 2014. 42(8):4868-81. PMCID: PMC4005663.
  11. Kvaratskhelia M, Sharma A, Larue RC, Serrao E, Engelman A. Molecular mechanisms of retroviral integration. Nucleic Acids Research 2014. 42(16):10209-25. PMCID: PMC4176367.
  12. *Sharma A, *Larue RC, Plumb MR, Malani N, Male F, Slaughter A, Kessl JJ, Shkriabai N, Coward E, Aiyer SS, Green PL, Wu L, Roth MJ, Bushman FD, Kvaratskhelia M. BET proteins promotes efficient murine leukemia virus integration at transcription start sites. PNAS 2013. 110(29):12036-41. *Co-first authors. PMCID: PMC3718171.
  13. Feng L, Sharma A, Slaughter A, Jena N, Koh Y, Shkriabai N, Larue RC, Patel PA, Mitsuya H, Kessl JJ, Engelman A, Fuchs JR, Kvaratskhelia M. The A128T resistance mutation reveals aberrant protein multimerization as the primary mechanism of action of allosteric HIV-1 integrase inhibitors. Journal of Biological Chemistry 2013. 288(22):15813-20. PMCID: PMC3668738.
  14. Chen C, Liu X, Boris-Lawrie K, Sharma A, Jeang KT. Cellular RNA helicases and HIV-1: Insights from genome-wide, proteomic, and molecular studies. Virus Research 2013. 171(2):357-65. PMCID: PMC3493675.
  15. Sharma A, Yilmaz A, Marsh K, Cochrane A, Boris-Lawrie K. Thriving under Stress: Selective Translation of HIV-1 Structural Protein mRNA during Vpr-Mediated Impairment of eIF4E Translation Activity. PLOS Pathogens 2012. 8(3):e1002612. PMCID: PMC3310836.
  16. Sharma A, and Boris-Lawrie K. Determination of host RNA helicases activity in viral replication. Methods in Enzymology 2012. Volume 511:405-35. PMID: 22713331. Book Chapter, ISBN: 978-0-12-396546-2.
  17. *Bolinger  C, *Sharma  A, Singh D, Boris-Lawrie K. RNA helicase A modulates translation of HIV-1 and infectivity of progeny virions. Nucleic Acids Research 2010. 38(5):1686-1696. *Co-first authors. PMCID: PMC2836548. Featured as cover article.