Hydrocortisone Replacement Therapy in Sick Foals

The purpose of this multi-centered study is to investigate the naturally acquired infection-induced activation of inflammatory molecules on the incidence and severity of "relative adrenal insufficiency" (RAI) in foals, as well as to determine if hydrocortisone replacement therapy will alter the activation of inflammatory molecules, reduce severity of disease, and improve survival in infected foals with RAI in a clinical hospital setting.