OSU Navigation Bar

The Ohio State University

College of Veterinary Medicine

Listen to this section

Research Summary

My primary research interest is focused on feline myocardial disease, assessment of LV diastolic function, all aspects of echocardiography, congestive heart failure, and evaluation of atrial function. I also study drugs that affect left ventricular diastolic function and left atrial and left atrial appendage function in cats short-term and long-term. Novel echocardiographic techniques such as strain and strain rate imaging are applied. In addition, pulmonary hypertension in dogs is another area of interest - its noninvasive diagnosis as well as its medical management.

Funded Research (Principal Investigator)

  • Title: Echocardiographic characterization of pulmonary venous flow in dogs.
    • Investigators: PI – Karsten Schober; Co-I’s – Virginia Luis Fuentes, Joanna Dukes McEwan, Anne French
    • Sponsor: German Academic Exchange Service
    • Type: Grant
    • Time: 1994-1995
    • Amount: Deutsch Mark 48,000 (approx. $25,000).
  • Title: Validation of noninvasive Doppler echocardiographic assessment of left ventricular diastolic function in cats.
    • Investigators: PI – Karsten Schober; Co-I’s – John Bonagura, Virginia Luis Fuentes
    • Agency: Max Kade Foundation
    • Type: Grant
    • Time: 1999-2000
    • Amount: $38,500.
  • Title: Prediction of Congestive Heart Failure in Dogs by Radiography, Blood Biochemical Analysis, and Doppler Echocardiography.
    • Investigators: PI – Karsten Schober; Co-I’s – John Bonagura, John Mattoon, Valeri Samii, Kathryn Meurs
    • Agency: Morris Animal Foundation
    • Type: Grant
    • Time: 2005-2008
    • Amount: $63,644.
  • Title: A study on the effects of atenolol versus diltiazem on LV diastolic function in asymptomatic cats with hypertrophic cardiomyopathy.
    • Investigators: PI – Karsten Schober, Co-I’s – John Bonagura, Virginia Luis Fuentes
    • Agency: The IAMS Company
    • Type: Grant
    • Time: 2004-2007
    • Amount: $11.907.
  • Title: Noninvasive Prediction of Congestive Heart Failure in Dogs by Doppler Echocardiography.
    • Investigators: PI – Karsten Schober; Co-I’s – John Bonagura, John Mattoon
    • Agency: Canine Research Funds, Ohio State University Funds
    • Type: Grant
    • Time: 2004-2005
    • Amount: $13.905.
  • Title: Use of cardiac Troponin I for early Detection of Myocardial Damage in Dairy Cows.
    • Investigators: PI – Karsten Schober, Co-I’s – Anita Varga, Michael Rings, Paul Stromberg
    • Agency: USDA Funds, Ohio State University Funds
    • Type: Grant
    • Time: 2007-2008
    • Amount: $13,125.
  • Title: Echocardiographic assessment of the mitral valve apparatus in cats with hypertrophic cardiomyopathy.
    • Investigators: PI – Karsten Schober, Co-I – Amanda Todd
    • Agency: Ohio State Research Foundation
    • Type: Summer Research Grant
    • Time: June to August 2007
    • Amount: $4,200
  • Title: Effects of bradycardic agents on heart rate in control cats and cats with hypertrophic cardiomyopathy: A dose finding study
    • Investigators: PI – Karsten Schober; Co-I’s – Richard Cober, DVM; John Bonagura, DVM, MS; Tony Buffington, DVM, PhD; Sabine Riesen, DVM; Brian Scansen, DVM, MS
    • Agency: ACVIM Foundation and Ohio Animal Health Foundation
    • Type: Grant
    • Time: 2008-2009
    • Amount: $15,760.
  • Title: Selective If current inhibition in cats with hypertrophic cardiomyopathy
    • Investigators: PI – Karsten Schober; Co-I’s – John Bonagura, DVM, MS; Tony Byffington, DVM, PhD; Robert Hamlin, MS, PhD; Sabine Riesen, DVM, MS; Cynthia Carnes, PharmD, PhD
    • Consultant: Arun Sridhar, BS, MS, PhD
    • Agency: ACVIM Foundation
    • Type: Grant
    • Time: 2 years (2009-2010)
    • Amount: $70,189
  • Title: Study on the Effects of Pimobendan on Hypertrophic Cardiomyopathy in Cats.
    • Investigators: Multicenter trial, PI for OSU VMC – Karsten Schober
    • Sponsor: Boerhringer Ingelheim Vetmedica, Inc.
    • Type: Contract
    • Time: 2010-2012
    • Amount: $113,118
  • Title: Clinical evaluation of a fully electronic stethoscope in cats.
    • Investigators: PI – Karsten Schober, DVM, PhD; Co-I’s – Keith Blass, DVM; Brian Scansen, DVM, MS; Lance Visser, DVM, MS; John Bonagura, DVM, MS
    • Sponsor: 3M
    • Type: Non-restricted gift
    • Time: 2011-2012
    • Amount: $10,000
  • Title: Left atrial size in cats with congestive heart failure. A study of 100 cats.
    • Investigators: PI – Karsten Schober, Ellen Wetli (VMII student), Tod Drost
    • Sponsor: Summer research program CVM
    • Type: Grant
    • Time: 2012
    • Amount: $4,200