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A complete PubMed list of Dr. Li Wu's publications are available HERE
Dr. Li Wu's publication
list and citation data on ResearcherID are available HERE
de Silva S, Wang F, Hake TS, Porcu P, Wong HK, Wu L. Downregulation of SAMHD1 expression correlates with promoter DNA methylation in Sézary syndrome patients. J Invest Dermatol. 2013 July 24. [Epub ahead of print]. Abstract
de Silva S, Hoy H, Hake TS, Wong HK, Porcu P, Wu L.
Promoter methylation regulates SAMHD1 gene expression in human CD4+ T
cells. J. Biol. Chem.2013; 288(13):9284-92. Abstract
Sharma A, Larue RC, Plumb MR, Malani N, Male F, Slaughter A, Kessl JJ, Shkriabai N, Coward E, Aiyer SS, Green PL, Wu L, Roth MJ, Bushman FD, Kvaratskhelia M. BET proteins promote efficient murine leukemia virus integration at transcription start sites. Proc Natl Acad Sci U S A. 2013; 110(29):12036-41. Abstract
Dong C, Zhao G, Zhong M, Yue Y, Wu L, Xiong S. RNA
sequencing and transcriptomal analysis of human monocyte to macrophage
differentiation. Gene. 2013; 519 (2): 279-287.
Barrios CS, Castillo L, Giam CZ, Wu L, Beilke MA.
Inhibition of HIV-1 replication by HTLV-1/2 Tax proteins in vitro. AIDS
Res Hum Retroviruses. 2013; Epub on March 6, 2013.
Zhai RR, Jiang AP, Wang HB, Ma L, Ren XX, Jiang JF, Wu L, Wei JF, Wang JH. Histamine enhances HIV-1-induced modulation of dendritic cells to skew naïve T cell differentiation toward regulatory T cells. Virology. 2013 May 4. [Epub ahead of print]
St Gelais C, de Silva S, Amie SM, Coleman C, Hoy H, Hollenbaugh J, Kim B, and Wu L. SAMHD1 restricts HIV-1 infection in dendritic cells (DCs) by dNTP depletion, but its expression in DCs and primary CD4+ T-lymphocytes cannot be upregulated by interferons. Retrovirology. 2012; 9, 105.
Coon S, Wang D, Wu L. Polymorphisms of the SAMHD1 gene are not associated with the infection and natural control of HIV-1 in Europeans and African Americans. AIDS Res Hum Retroviruses. 2012, 28(12):1565-73. Epub 2012 Jun 1.
Zhang C, de Silva S, Wang J, Wu L. Co-evolution of primate SAMHD1 and lentivirus Vpx leads to the loss of the vpx gene in HIV-1 ancestor. PLoS One. 2012;7(5):e37477. Epub 2012 May 4.
de Silva S,
Planelles V, Wu L. Differential effects of Vpr on single-cycle and
spreading HIV-1 infections in CD4+ T-cells and dendritic cells. PLoS One. 2012;7(5):e35385. Epub 2012 May 3.
St Gelais C,
Coleman CM, Wang JH, Wu L. HIV-1 Nef enhances dendritic cell-mediated
viral transmission to CD4+ T cells and promotes T-cell activation. PLoS One.
2012; 7(3):e34521. Epub 2012 Mar 30.
Kessl JJ, Jena N, Koh Y, Taskent-Sezgin H, Slaughter A, Feng L, de Silva S, Wu L, Le Grice SF, Engelman A, Fuchs JR, Kvaratskhelia M. A multimode, cooperative mechanism of action of allosteric HIV-1 integrase inhibitors. J. Biol. Chem. 2012; 287(20):16801-11. Abstract
Zhu Y, Chen G, Lv F, Wang X, Ji X, Xu Y, Sun J, Wu L, Zheng YT, Gao G. Zinc-finger antiviral protein inhibits HIV-1 infection by selectively targeting multiply spliced viral mRNAs for degradation. Proc Natl Acad Sci U S A. 2011;108:15834.
Coleman CM, Spearman P, Wu L. Tetherin does not significantly restrict dendritic cell-mediated HIV-1 transmission and its expression is upregulated by newly synthesized HIV-1 Nef. Retrovirology. 2011; 8:26.
Qin Y, Li Y, Liu W, Tian R, Guo Q, Li S, Li H, Zhang D, Zheng Y, Wu L, Lan K, Wang J. Penicillium marneffei-stimulated dendritic cells enhance HIV-1 trans-infection and promote viral infection by activating primary CD4+ T cells. PLoS One. 2011;6(11):e27609.
Raghavendra NK, Shkriabai N, Graham RLJ, Hess S, Kvaratskhelia M, Wu L. Identification of host proteins associated with HIV-1 preintegration complexes isolated from infected CD4+ cells. Retrovirology. 2010; 7:66. Abstract
Blanchet FP, Moris A, Nikolic DS, Lehmann M, Cardinaud S, Stalder R, Garcia E, Dinkins C, Leuba F, Wu L, Schwartz O, Deretic V, Piguet V. Human immunodeficiency virus-1 inhibition of immunoamphisomes in dendritic cells impairs early innate and adaptive immune responses. Immunity. 2010 May 28;32(5):654-69.
Chung NP, Breun SK, Bashirova A, Baumann JG, Martin TD, Karamchandani JM, Rausch JW, Le Grice SF, Wu L, Carrington M, KewalRamani VN. HIV-1 transmission by dendritic cell-specific ICAM-3-grabbing nonintegrin (DC-SIGN) is regulated by determinants in the carbohydrate recognition domain that are absent in liver/lymph node-SIGN (L-SIGN). J Biol Chem. 2010;15;285(3):2100-12.
Wang JH, Kwas C, Wu L. Intercellular adhesion molecule 1 (ICAM-1), but not ICAM-2 and -3, is important for dendritic cell-mediated human immunodeficiency virus type 1 transmission. J Virol. 2009; 83(9):4195-204.
Dong C, Kwas C, Wu L. Transcriptional restriction of human immunodeficiency virus type 1 gene expression in undifferentiated primary monocytes. J Virol. 2009; 83(8):3518-27.
Kyei GB, Dinkins C, Davis AS, Roberts E, Singh SB, Dong C, Wu L, Kominami E, Ueno T, Yamamoto A, Federico M, Panganiban A, Vergne I, and Deretic V. Autophagy pathway intersects with HIV-1 biosynthesis and regulates viral yields in macrophages. J. Cell Biol. 2009; 186: 255-268. Abstract
Wang JH, Wells C, Wu L. Macropinocytosis and cytoskeleton contribute to dendritic cell-mediated HIV-1 transmission to CD4+ T cells. Virology. 2008; 381(1):143-54.
Janas AM, Dong C, Wang JH, Wu L. Productive infection of human immunodeficiency virus type 1 in dendritic cells requires fusion-mediated viral entry. Virology. 2008; 375(2):442-51.
Dong C, Janas AM, Wang JH, Olson WJ, and Wu L. Characterization of human immunodeficiency virus type 1 replication in immature and mature dendritic cells reveals dissociable cis- and trans-infection. J Virol. 2007; 81:(20) 11352-62
Wang JH, Janas AM, Olson WJ, Wu L. Functionally distinct transmission of human immunodeficiency virus type 1 mediated by immature and mature dendritic cells. J Virol. 2007; 81(17):8933-43
About Journal Cover Illustration
Wang JH, Janas AM, Olson WJ, KewalRamani VN, Wu L. CD4 coexpression regulates DC-SIGN-mediated transmission of human immunodeficiency virus type 1. J Virol. 2007; 81(5):2497-507
Wu L, Martin TD, Han YC, Breun SK, KewalRamani VN. Trans-dominant cellular inhibition of DC-SIGN-mediated HIV-1 transmission. Retrovirology. 2004; 28;1(1):14
Wu L, Martin TD, Carrington M, KewalRamani VN. Raji B cells, misidentified as THP-1 cells, stimulate DC-SIGN-mediated HIV transmission. Virology. 2004; 5;318(1):17-23.
McDonald D, Wu L, Bohks SM, KewalRamani VN, Unutmaz D, Hope TJ. Recruitment of HIV and its receptors to dendritic cell-T cell junctions. Science. 2003;300(5623):1295-7.
Bashirova AA, Wu L, Cheng J, Martin TD, Martin MP, Benveniste RE, Lifson JD, KewalRamani VN, Hughes A, Carrington M. Novel member of the CD209 (DC-SIGN) gene family in primates. J Virol. 2003;77(1):217-27
Wu L, Martin TD, Vazeux R, Unutmaz D, KewalRamani VN. Functional evaluation of DC-SIGN monoclonal antibodies reveals DC-SIGN interactions with ICAM-3 do not promote human immunodeficiency virus type 1 transmission. J Virol. 2002;76(12):5905-14.
Wu L, Bashirova AA, Martin TD, Villamide L, Mehlhop E, Chertov AO, Unutmaz D, Pope M, Carrington M, KewalRamani VN. Rhesus macaque dendritic cells efficiently transmit primate lentiviruses independently of DC-SIGN. Proc Natl Acad Sci U S A. 2002;99(3):1568-73
Bashirova AA, Geijtenbeek TB, van Duijnhoven GC, van Vliet SJ, Eilering JB, Martin MP, Wu L, Martin TD, Viebig N, Knolle PA, KewalRamani VN, van Kooyk Y, Carrington M. A dendritic cell-specific intercellular adhesion molecule 3-grabbing nonintegrin (DC-SIGN)-related protein is highly expressed on human liver sinusoidal endothelial cells and promotes HIV-1 infection. J. Exp. Med. 2001; 193: 671-678. Abstract
Reviews & Book Chapters
Wu L. Samhd1 knockout mice: modeling retrovirus restriction in vivo. Retrovirology. 2013; 10:142. Abstract
Wu L. Cellular and biochemical mechanisms of the retroviral restriction factor SAMHD1. ISRN Biochemistry. 2013; Article ID 728392, 11 pages. doi:10.1155/2013/728392. Abstract
Wu L. SAMHD1: a new contributor to HIV-1 restriction in resting CD4+ T-cells. Retrovirology 2012, 9:88
Coleman CM, Gelais CS, Wu L. Cellular and viral mechanisms of HIV-1 transmission mediated by dendritic cells. Adv Exp Med Biol. 2013; 762:109-130.
Book series: Topics in HIV and AIDS. HIV Interactions with Dendritic Cells: Infection and Immunity. Edited by Wu L. and Schwartz O. Springer, New York. 2013. Weblink
Wu L. The role of monocyte-lineage cells in HIV persistence:
mechanisms and progress. Journal of Microbes and Infections. 2011; 6
(3): 129-132. Abstract
St Gelais, C., and Wu L. SAMHD1: a new insight into HIV-1 restriction in myeloid cells. Retrovirology. 2011; 8:55
de Silva S., and Wu L. TRIM5 acts as more than a retroviral restriction
factor. Viruses. 2011; 3(7):1204-1209.
Coleman CM, Wu L. HIV interactions with monocytes and dendritic cells: viral latency and reservoirs. Retrovirology 2009, 6:51
Janas AM, Wu L. HIV-1 interactions with cells: from viral binding to cell-cell transmission. Curr Protoc Cell Biol. 2009; Chapter 26:Unit 26.5
Wu L. Biology of HIV mucosal transmission. Curr Opin HIV AIDS. 2008; 3(5):534-540
Wu L, KewalRamani VN. Dendritic-cell interactions with HIV: infection and viral dissemination. Nat Rev Immunol. 2006; 6(11):859-68