Publications
Research Articles
de Silva S, Hoy H, Hake TS, Wong HK, Porcu P, Wu L.
Promoter methylation regulates SAMHD1 gene expression in human CD4+ T
cells. J. Biol. Chem.2013; 288(13):9284-92.
Abstract
Dong C, Zhao G, Zhong M, Yue Y, Wu L, Xiong S. RNA
sequencing and transcriptomal analysis of human monocyte to macrophage
differentiation. Gene. 2013; 519 (2): 279-287.
Abstract
Barrios CS, Castillo L, Giam CZ, Wu L, Beilke MA.
Inhibition of HIV-1 replication by HTLV-1/2 Tax proteins in vitro. AIDS
Res Hum Retroviruses. 2013; Epub on March 6, 2013.
Abstract
Zhai RR, Jiang AP, Wang HB, Ma L, Ren XX, Jiang JF, Wu
L, Wei JF, Wang JH. Histamine enhances HIV-1-induced modulation of
dendritic cells to skew naïve T cell differentiation toward regulatory T
cells. Virology. 2013 May 4. [Epub ahead of print]
Abstract
St Gelais C, de Silva S,
Amie SM, Coleman C, Hoy H, Hollenbaugh J, Kim B, and Wu L. SAMHD1
restricts HIV-1 infection in dendritic cells (DCs) by dNTP depletion, but its expression in DCs and
primary CD4+ T-lymphocytes cannot be upregulated by
interferons. Retrovirology. 2012; 9, 105.
Abstract
Kessl JJ, Jena N, Koh Y, Taskent-Sezgin H, Slaughter A, Feng
L, de Silva S, Wu L, Le Grice SF, Engelman A, Fuchs JR, Kvaratskhelia M. A
multimode, cooperative mechanism of action of allosteric HIV-1 integrase
inhibitors. J. Biol. Chem. 2012; 287(20):16801-11.
Abstract
Coon S, Wang
D, Wu L. Polymorphisms of the SAMHD1 gene are not associated with the
infection and natural control of HIV-1 in Europeans and African Americans. AIDS
Res Hum Retroviruses. 2012, Dec; 28(12):1565-73.
Abstract
Zhang C, de
Silva S, Wang J, Wu L. Co-evolution of primate SAMHD1 and lentivirus Vpx
leads to the loss of the vpx gene in HIV-1 ancestor. PLoS One. 2012;7(5):e37477.
Epub 2012 May 4.
Abstract
de Silva S,
Planelles V, Wu L. Differential effects of Vpr on single-cycle and
spreading HIV-1 infections in CD4+ T-cells and dendritic cells. PLoS One. 2012;7(5):e35385. Epub 2012 May 3.
Abstract
St Gelais C,
Coleman CM, Wang JH, Wu L. HIV-1 Nef enhances dendritic cell-mediated
viral transmission to CD4+ T cells and promotes T-cell activation. PLoS One.
2012; 7(3):e34521. Epub 2012 Mar 30.
Abstract
Qin Y, Li Y, Liu W, Tian R, Guo Q, Li S, Li H, Zhang D,
Zheng Y, Wu L, Lan K, Wang J. Penicillium marneffei-stimulated dendritic cells
enhance HIV-1 trans-infection and promote viral infection by activating primary
CD4+ T cells. PLoS One. 2011;6(11):e27609.
Abstract
Zhu Y, Chen G, Lv F, Wang X, Ji X, Xu Y, Sun J, Wu L, Zheng YT, Gao G.
Zinc-finger antiviral protein inhibits HIV-1 infection by selectively targeting
multiply spliced viral mRNAs for degradation. Proc Natl Acad Sci U S A.
2011;108:15834.
Abstract
Coleman CM, Spearman P, Wu L. Tetherin does not significantly restrict dendritic cell-mediated HIV-1 transmission and its expression is upregulated by newly synthesized HIV-1 Nef. Retrovirology. 2011; 8:26.
Abstract
Raghavendra NK, Shkriabai N, Graham RLJ, Hess S, Kvaratskhelia M, Wu L. Identification of host proteins associated with HIV-1 preintegration complexes isolated from infected CD4+ cells. Retrovirology. 2010; 7:66.
Abstract
Blanchet FP, Moris A, Nikolic DS, Lehmann M, Cardinaud S, Stalder R, Garcia E, Dinkins C, Leuba F, Wu L, Schwartz O, Deretic V, Piguet V. Human immunodeficiency virus-1 inhibition of immunoamphisomes in dendritic cells impairs early innate and adaptive immune responses. Immunity. 2010 May 28;32(5):654-69.
Abstract
Chung NP, Breun SK, Bashirova A, Baumann JG, Martin TD, Karamchandani JM, Rausch JW, Le Grice SF, Wu L, Carrington M, KewalRamani VN. HIV-1 transmission by dendritic cell-specific ICAM-3-grabbing nonintegrin (DC-SIGN) is regulated by determinants in the carbohydrate recognition domain that are absent in liver/lymph node-SIGN (L-SIGN). J Biol Chem. 2010;15;285(3):2100-12.
Abstract
Wang JH, Kwas C, Wu L. Intercellular adhesion molecule 1 (ICAM-1), but not ICAM-2 and -3, is important for dendritic cell-mediated human immunodeficiency virus type 1 transmission. J Virol. 2009; 83(9):4195-204.
Abstract
Dong C, Kwas C, Wu L. Transcriptional restriction of human immunodeficiency virus type 1 gene expression in undifferentiated primary monocytes. J Virol. 2009; 83(8):3518-27.
Abstract
Wang JH, Wells C, Wu L. Macropinocytosis and cytoskeleton contribute to dendritic cell-mediated HIV-1 transmission to CD4+ T cells. Virology. 2008; 381(1):143-54.
Abstract
Janas AM, Dong C, Wang JH, Wu L. Productive infection of human immunodeficiency virus type 1 in dendritic cells requires fusion-mediated viral entry. Virology. 2008; 375(2):442-51.
Abstract
Dong C, Janas AM, Wang JH, Olson WJ, and Wu L. Characterization of human immunodeficiency virus type 1 replication in immature and mature dendritic cells reveals dissociable cis- and trans-infection. J Virol. 2007; 81:(20) 11352-62
Abstract
Wang JH, Janas AM, Olson WJ, Wu L. Functionally distinct transmission of human immunodeficiency virus type 1 mediated by immature and mature dendritic cells. J Virol. 2007; 81(17):8933-43
Abstract
About Journal Cover Illustration
Wang JH, Janas AM, Olson WJ, KewalRamani VN, Wu L. CD4 coexpression regulates DC-SIGN-mediated transmission of human immunodeficiency virus type 1. J Virol. 2007; 81(5):2497-507
Abstract
Wu L, Martin TD, Han YC, Breun SK, KewalRamani VN. Trans-dominant cellular inhibition of DC-SIGN-mediated HIV-1 transmission. Retrovirology. 2004; 28;1(1):14
Abstract
Wu L, Martin TD, Carrington M, KewalRamani VN. Raji B cells, misidentified as THP-1 cells, stimulate DC-SIGN-mediated HIV transmission. Virology. 2004; 5;318(1):17-23.
Abstract
McDonald D, Wu L, Bohks SM, KewalRamani VN, Unutmaz D, Hope TJ. Recruitment of HIV and its receptors to dendritic cell-T cell junctions. Science. 2003;300(5623):1295-7.
Abstract
Bashirova AA, Wu L, Cheng J, Martin TD, Martin MP, Benveniste RE, Lifson JD, KewalRamani VN, Hughes A, Carrington M. Novel member of the CD209 (DC-SIGN) gene family in primates. J Virol. 2003;77(1):217-27
Abstract
Wu L, Martin TD, Vazeux R, Unutmaz D, KewalRamani VN. Functional evaluation of DC-SIGN monoclonal antibodies reveals DC-SIGN interactions with ICAM-3 do not promote human immunodeficiency virus type 1 transmission. J Virol. 2002;76(12):5905-14.
Abstract
Wu L, Bashirova AA, Martin TD, Villamide L, Mehlhop E, Chertov AO, Unutmaz D, Pope M, Carrington M, KewalRamani VN. Rhesus macaque dendritic cells efficiently transmit primate lentiviruses independently of DC-SIGN. Proc Natl Acad Sci U S A. 2002;99(3):1568-73
Abstract
Reviews & Book Chapters
Wu L. SAMHD1: a new contributor to HIV-1 restriction in resting CD4+ T-cells. Retrovirology 2012, 9:88
Abstract
Coleman CM, Gelais
CS, Wu L. Cellular and viral mechanisms of HIV-1 transmission
mediated by dendritic cells. Adv Exp Med Biol. 2013;
762:109-130.
Abstract
Book HIV Interactions with Dendritic Cells: Infection and Immunity. Edited by Wu L. and Schwartz O. Springer, New York. 2013. Weblink
St Gelais, C., and Wu L. SAMHD1: a new insight into HIV-1 restriction
in myeloid cells. Retrovirology. 2011; 8:55
Abstract
de Silva S., and Wu L. TRIM5 acts as more than a retroviral restriction
factor. Viruses. 2011; 3(7):1204-1209.
Abstract
Coleman CM, Wu L. HIV interactions with monocytes and dendritic cells: viral latency and reservoirs. Retrovirology 2009, 6:51
Abstract
Janas AM, Wu L. HIV-1 interactions with cells: from viral binding to cell-cell transmission. Curr Protoc Cell Biol. 2009; Chapter 26:Unit 26.5
Abstract
Wu L. Biology of HIV mucosal transmission. Curr Opin HIV AIDS. 2008; 3(5):534-540
Abstract
Wu L, KewalRamani VN. Dendritic-cell interactions with HIV: infection and viral dissemination. Nat Rev Immunol. 2006; 6(11):859-68
Abstract
