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Publications (last three to five years)

Recemt Peer Reviewed Articles (selected from a total of 47 peer-reviewed publications)

  1. Jaime-Ramirez AC, Mundy-Bosse BL, Kondadasula S, Jones NB, Roda JM, Mani A, Parihar R, Karpa V, Papenfuss TL, LaPerle KM, Biller E, Lehman A, Chaudhury AR, Jarjoura D, Burry RW, Carson WE. IL-12 enhances the antitumor actions of trastuzumab via NK cell IFN-Y production. Journal of Immunology 186: 3401-3409, 2011.
  2. Gravaghi C, La Perle KM, Ogrodwski P, Kang JX, Quimby F, Lipkin M, Lamprecht SA. Cox-2 expression, PGE(2) and cytokines production are inhibited by endogenously synthesized n-3 PUFAs in inflamed colon of fat-1 mice. Journal of Nutritional Biochemistry 22: 360-365, 2011.
  3. Munson L, Craig LE, Miller MA, Kock ND, Simpson ND, Wellman ML, Sharkey LC and Birkebak for the American College of Veterinary Pathologists Training Program Development Task Force (Ackermann MR, Birkebak TA, Blanchard TW, Andreasen CB, Carmichael KP, Cline JM, Cockerell GL, Craig LE, Dunn DG, Harris RK, Kock ND, La Perle KMD, Malarkey DE, Miller MA, Munson L, Rudmann DG, Sharkey LC, Simpson RM, Terrell SP, Tornquist SJ, Weiser MG, Wellman ML). Elements of good training in anatomic pathology. Veterinary Pathology 47: 995-1002, 2010.
  4. Jones GN, Pringle DR, Yin Z, Carlton MM, Powell KA, Weinstein MB, Toribio RE, La Perle KM, Kirschner LS. Neural crest-specific loss of Prkar1a causes perinatal lethality resulting from defects in intramembranous ossification. Molecular Endocrinology 24: 1559-1568, 2010.
  5. Roepke RK, Purtell K, King EC, La Perle KMD, Lerner DJ, Abbott GW. Targeted deletion of Kcne2 causes gastritis cystica profunda and gastric neoplasia. PLoS One 5: e11451, 1-10, 2010.
  6. Wang H, Karikomi M, Naidu S, Rajmohan R, Caserta E, Chen HZ, Rawahneh M, Moffitt J, Stephens JA, Fernandez SA, Weinstein M, Wang D, Sadee W, La Perle K, Stromberg P, Rosol TJ, Eng C, Ostrowski MC, Leone G. Allele-specific tumor spectrum in Pten knockin mice. Proceedings of the National Academy of Sciences of the USA 107: 5142-5147, 2010.
  7. Bouley D, Meyerholz D, Sellers R, Boyd K, La Perle K. Where’s the mouse pathology training? Veterinary Pathology 46: 1245-1247, 2009.
  8. Chen X, Mitsutake N, LaPerle K, Akeno N, Zanzonico P, Longo VA, Mitsukae S, Kimura ET, Geiger H, Santos E, Wendel HG, Franco A, Knauf JA, Fagin JA. Endogenous expression of Hras(G12V) induces developmental defects and neoplasms with copy number imbalances of the oncogene. Proceedings of the National Academy of Sciences of the USA 106: 7979-7984, 2009.
  9. Postel EH, Zou X, Notterman DA, La Perle KMD. Double knockout Nme1/Nme2 mouse model suggests a critical role for NDP kinases in erythroid development. Molecular and Cellular Biochemistry 329: 45-40, 2009.
  10. Santos EB, Yeh R, Lee J, Nikhamin Y, Punzalan B, Punzalan B, La Perle K, Larson SM, Sadelain M, Brentjens R. Sensitive in vivo imaging of T cells using a membrane-bound Gaussia princeps luciferase. Nature Medicine 15: 338-344, 2009.
  11. Postel EH, Wohlman I, Zou X, Juan T, Sun N, D’Agostin D, Cuellar M, Choi T, Notterman DA, La Perle KMD. Targeted deletion of Nm23/nucleoside diphosphate kinase A and B reveals their requirement for definitive erythropoiesis in the mouse embryo. Developmental Dynamics 238: 775-787, 2009.
  12. Gravaghi C, Bo J, La Perle KMD, Quimby F, Kucherlapati R, Edelmann W, Lamprecht SA. Obesity enhances gastrointestinal tumorigenesis in Apc mutant mice. International Journal of Obesity 32: 1716-1719, 2008.
  13. Brentjens RJ, Santos E, Nikhamin Y, Yeh R, Matsushita M, La Perle K, Quintás-Cardama A, Larson S, Sadelain M. Successful eradication of systemic acute lymphoblastic leukemia xenografts by genetically targeted T cells. Clinical Cancer Research 13: 5426-5435, 2007.
  14. Cohen JK, Li-Qun Cai, Zhu Y-S, La Perle KMD. Pancreaticoduodenal arterial rupture and hemoabdomen in ACI/SegHsd rats with polyarteritis nodosa. Comparative Medicine 57: 370-376, 2007.
  15. McIntyre A, La Perle KMD. Hermaphroditism in 3 chimeric mice. Veterinary Pathology 44: 249-252, 2007.
  16. Mutlu AD, Cavallin LE, Vincent L, Chiozzini C, Eroles P, Duran EM, Asgari Z, Hooper AT, La Perle KMD, Hilsher C, Gao S-J, Dittmer DP, Rafii S, Mesri EA. In vivo-restricted and reversible malignancy induced by human herpesvirus-8 KSHV: A cell and animal model of virally induced Kaposi’s sarcoma.     Cancer Cell 11: 245-258, 2007.

Book Chapters

  1. La Perle KMD and Couto SS. Mouse Models of Hematologic Malignancies. In C. H. Dunphy (Ed.), Molecular Pathology of Hematolymphoid Malignancies, Springer, 2010, New York, pp. 203-208.
  2. La Perle KMD and Capen CC. Endocrine System. In M. D. McGavin and J. F. Zachary (Eds.), Pathologic Basis of Veterinary Disease, 4th Edition, 2007, Mosby Elsevier, St. Louis, pp. 693-741.
  3. La Perle KMD and Jhiang SM. Iodine: Symporter and oxidation, thyroid hormone biosynthesis. In H. L. Henry and A. W. Norman (Eds.), Encyclopedia of Hormones, Volume 2 of 3, 2003, Academic Press, San Diego, pp. 517-522.