Professional Activities

Research Interests

(See the link to Videos on Research Program)

  • Parathyroid Hormone-Related Protein (PTHrP):
    • Pathogenesis in humoral hypercalcemia of malignancy
    • Regulation in normal and neoplastic keratinocytes
    • Regulation in lactation and mammary carcinomas
    • Development of a Cre/LoxP Mammary Gland Specific "Knock-Out" Transgenic Mice
    • Regulation of mRNA expression and stability by transforming growth factor-beta
    • Role in cancer metastases in bone
    • Role in bone resorption associated with Human T-Lymphotropic-I Virus infection and canine lymphoma
    • Regulation of PTHrP mRNA expression by Tax and HTLV-1 virus
  • Animal Models of Human Disease:
    • Paraneoplastic Syndromes
    • Endocrinology
    • Bone Disease, Bone Remodeling, Bone Metastasis
    • Prostate Cancer and Osteoblastic Metastasis
    • Breast, Lung, and Head & Neck Cancer and Osteolytic Bone Metastasis

Consulting

  • Endocrine Pathology
  • Reproductive Pathology
  • Bone Diseases and Bone Remodeling
  • Cancer and Metastasis (emphasis on bone metastasis)
    • Prostate Cancer
    • Breast Cancer
    • Head and Neck Cancer
    • Lymphoma

Boards and Councils

  • 2010-present: Council for Research, AVMA (national election)
  • 2008-present: External Advisory Board, North Carolina State University Center for Comparative Medicine and Translational Research
  • 2007-2010: NIH Council, National Center for Research Resources (NCRR) Advisory Board
  • 2008-2010: USDA Advisory Board, National Agricultural Research, Extension, Education, and Economics Advisory Board (NAREEEAB)
  • 2007-2011: Board of Scientific Advisors, Pathology Experts, LLC (Basel)
  • 2006-2011: External Advisory Board, University of Michigan NIH Program Project Grant on Skeletal Metastases
  • 2006-present: Board of Trustees, The Wilds (conservation of exotic animals)
  • 2005-2008: Board of Trustees (ex officio), Ohio Veterinary Medical Association
  • 2005-2008: Board of Trustees (ex officio), Ohio Livestock Coalition
  • 2005-2008: Board of Trustees, OSU College of Veterinary Medicine Alumni Society
  • 2003-2004: Board of Trustees, Scitech (Science Research & Technology Park for OSU)
  • 2003-2004: Board of Trustees (President), Ohio State University Research Foundation Board
  • 2003-2004: Council for Higher Education, Ohio Board of Regents
  • 2003-2004: Governing Board, Ohio Supercomputer Center
  • 2003-2004: Board of Trustees, Edison Welding Institute
  • 2003-2004: Board of Directors, Ohio Aerospace Institute (OAI)
  • 2003-2004: Ohio Polymer Strategy Council
  • 2003-2004: Board of Directors, Transportation Research Center
  • 2003-2004: Council on Research Policy and Graduate Education (CRPG, NASULGC)
  • 2003-2004: Committee on Institutional Cooperation (CIC) for Senior Research Officers