Professional Activities
Research Interests
(See the link to Videos on Research Program)
- Parathyroid Hormone-Related Protein (PTHrP):
- Pathogenesis in humoral hypercalcemia of malignancy
- Regulation in normal and neoplastic keratinocytes
- Regulation in lactation and mammary carcinomas
- Development of a Cre/LoxP Mammary Gland Specific "Knock-Out" Transgenic Mice
- Regulation of mRNA expression and stability by transforming growth factor-beta
- Role in cancer metastases in bone
- Role in bone resorption associated with Human T-Lymphotropic-I Virus infection and canine lymphoma
- Regulation of PTHrP mRNA expression by Tax and HTLV-1 virus
- Animal Models of Human Disease:
- Paraneoplastic Syndromes
- Endocrinology
- Bone Disease, Bone Remodeling, Bone Metastasis
- Prostate Cancer and Osteoblastic Metastasis
- Breast, Lung, and Head & Neck Cancer and Osteolytic Bone Metastasis
Consulting
- Endocrine Pathology
- Reproductive Pathology
- Bone Diseases and Bone Remodeling
- Cancer and Metastasis (emphasis on bone
metastasis)
- Prostate Cancer
- Breast Cancer
- Head and Neck Cancer
- Lymphoma
Boards and Councils
- 2010-present: Council for Research, AVMA (national election)
- 2008-present: External Advisory Board, North Carolina State University Center for Comparative Medicine and Translational Research
- 2007-2010: NIH Council, National Center for Research Resources (NCRR) Advisory Board
- 2008-2010: USDA Advisory Board, National Agricultural Research, Extension, Education, and Economics Advisory Board (NAREEEAB)
- 2007-2011: Board of Scientific Advisors, Pathology Experts, LLC (Basel)
- 2006-2011: External Advisory Board, University of Michigan NIH Program Project Grant on Skeletal Metastases
- 2006-present: Board of Trustees, The Wilds (conservation of exotic animals)
- 2005-2008: Board of Trustees (ex officio), Ohio Veterinary Medical Association
- 2005-2008: Board of Trustees (ex officio), Ohio Livestock Coalition
- 2005-2008: Board of Trustees, OSU College of Veterinary Medicine Alumni Society
- 2003-2004: Board of Trustees, Scitech (Science Research & Technology Park for OSU)
- 2003-2004: Board of Trustees (President), Ohio State University Research Foundation Board
- 2003-2004: Council for Higher Education, Ohio Board of Regents
- 2003-2004: Governing Board, Ohio Supercomputer Center
- 2003-2004: Board of Trustees, Edison Welding Institute
- 2003-2004: Board of Directors, Ohio Aerospace Institute (OAI)
- 2003-2004: Ohio Polymer Strategy Council
- 2003-2004: Board of Directors, Transportation Research Center
- 2003-2004: Council on Research Policy and Graduate Education (CRPG, NASULGC)
- 2003-2004: Committee on Institutional Cooperation (CIC) for Senior Research Officers
