Examine the natural history, evolution, and genomic diversity of avian-origin influenza A viruses and the epidemiology of influenza A virus infections in waterfowl using parts of the Mississippi Migratory Bird Flyway.
Gain insight into how antigenic and genomic diversity of influenza A viruses are maintained in wild bird populations.
Add to a baseline from which to detect the appearance and emergence of unique or rare genomic segments or constellations that potentially could present an increased threat to animal and human health.
Expand the wild bird-origin influenza A virus repository.
Submit isolates to JCVI for full length sequencing and subsequent placement of sequence data into GenBank and the IRD for use by scientists around the world.
Merge data from previous years to draw conclusions regarding influenza A viruses circulating in wild birds in the Mississippi flyway.
The epidemiology of bidirectional transmission of influenza A viruses at the human-swine interface at agricultural fairs.
Conduct surveillance for influenza A virus circulating among clinically normal swine at agricultural fairs and exhibitions.
Conduct diagnostic testing of each sample for the presence of influenza A virus, including virus isolation and RRT-PCR, and maintain a repository of swine-origin isolates.
Determine the HA and NA subtypes and submit isolates for full length genomic sequencing and subsequent placement into GenBank and IRD for use by scientists around the world.
Evaluate genomic segments to determine differences in the genomic constellations of the recovered viruses.