Acute infectious diarrheal diseases are increasingly recognized as a significant global public health problem despite major advances and improvements in hygiene, the quality of food, water and sanitation, detection of foodborne pathogens, and the surveillance systems during the last century. They not only cause millions of gastroenteritis cases annually in individual countries, but also are a social and economic burden. The continued emergence, development and spread of antimicrobial resistance among these diarrheal diseases are also a major concern. The proposed research program is intended to develop new and improved diagnostic methods and related materials and tools as systems for rapid, sensitive and definitive detection, diagnosis and characterization of some of the most important causes of infectious bacterial and viral diarrhea. The working hypothesis for this research project is development of rapid and sensitive identification and tracking system for bacterial and viral diarrheal pathogens. These methods will enable the development and implementation of science-based measures to detect, track, eliminate or reduce diarrheal and antimicrobial resistant pathogens in the population.
This project will involve: