- Age: Adult
- Sex: Female
- Breed: Nude mouse (Mus musculus) used as a sentinel
Mouse noted to have marked abvominal distention. BCS 1/5; QAR; hunched in cage with rough hair coat
See Figures 4-6. The heart, lungs, thymus, lymph nodes,
kidneys, liver, spleen, pancreas, stomach and intestines, ovaries and uterus, adrenal
glands and brain were similarly affected.
- What is a nude mouse?
- What is a sentinel mouse?
- What is your interpretation of the hemogram?
- Which domestic veterinary species has a normal white blood cell differential pattern
similar to the mouse?
- What are the 4 gross abnormalities depicted in Figure 3?
- What tissues are depicted in Figures 4, 5 and 6, respectively?
- What’s your diagnosis?
- What is the purple globular material within vascular lumens? This is indicative of a "syndrome" that is typically diagnosed ante mortem in domestic veterinary species
and humans!..what is the name of it?
- What other conditions is it associated with?
- What are 3 broad mechanisms contributing to the morbidity and mortality (had she
died spontaneously instead of being euthanized) of this mouse?