Dr. Tony Buffington and Researchers Discover Biomarker

Research article appears in journal Analyst

Dr. Tony Buffington, professor of veterinary clinical sciences at Ohio State, and his research team have discovered a biomarker in cats and humans that may lead to better treatments for some chronic pain syndromes.

The biomarker, found in the blood, might signal both species' susceptibility to a painful bladder disorder called interstitial cystitis, a condition that is often difficult to diagnose. The findings lead researchers to believe that the disorder originates in the brain because of the way an essential amino acid is broken down in individuals with the specified biomarker.

Dr. Buffington believes this biomarker may be the underlying vulnerability that results in IC, and possibly in other chronic pain disorders such as irritable bowl syndrome and fibromyalgia. This new understanding may lead to improved methods of diagnosis, treatment and even prevention strategies.

The research appears in the current issue of the journal Analyst. The university news release can be viewed here.

Various media outlets have covered the findings of the research. The United Press International story can be viewed here, and Science Daily's article can be viewed here.

By Michelle Fehribach

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About the College of Veterinary Medicine at Ohio State

Founded in 1885, The Ohio State University College of Veterinary Medicine is ranked fifth in the nation and includes more than 1,000 faculty, staff and students in the Departments of Veterinary Biosciences, Veterinary Clinical Sciences, and Veterinary Preventive Medicine. The Veterinary Medical Center is one of the largest specialty referral centers in the world, with more than 35,000 farm, equine, and companion animal patients each year. A nationally-recognized ambulatory practice and teaching unit in Marysville, Ohio provides farm animal experience to every veterinary student, and the Food Animal Health Research Program in Wooster, OH focuses on detection, control, and prevention of disease. Located on the only campus in the country with a comprehensive medical center offering seven health sciences colleges, we admit up to 162 veterinary students per class, and offer a new comprehensive graduate program in Veterinary and Comparative Medicine as well as a unique Master’s degree in Veterinary Public Health, in partnership with the College of Public Health. http://vet.osu.edu.