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Comparative Pathology and Mouse Phenotyping Shared Resource
The Comparative Pathology and Mouse Phenotyping Shared Resource (CPMPSR) provides expert, readily available and affordable experimental pathology support to investigators utilizing animal models to study human disease. Comparative pathologists affiliated with the CPMPSR are familiar with normal anatomy and physiology, as well as background age- and strain-related lesions of various animal models. Recognition of lesions and their interpretation in the context of individual investigations provides a critical component to research incorporating animal models. Services include comprehensive macroscopic and microscopic examinations of various species of laboratory animals with an emphasis on the phenotypic characterization of newly produced lines of genetically engineered mice. Additional services include hematology, clinical chemistry, radiography; and, in conjunction with the Histology and Immunohistochemistry Core, routine frozen and paraffin slide preparation as well as tissue microarray preparation and special histochemical and immunohistochemical staining. In addition, the CPMPSR provides a referral service to experienced scientists within the OSU research community providing expertise in animal model development, experimental design, optimal sample collection, and data interpretation.
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