Recent advances in genetics and molecular biology have allowed researchers to identify genes and molecules associated with particular human diseases. This knowledge has led to the development of more effective therapies for these diseases. Examples include new treatments for breast cancer, lung cancer, asthma, multiple sclerosis, and rheumatoid arthritis. We have only begun to investigate the genetics and molecular biology of canine diseases, but based on advances in human medicine, a great opportunity exists to make similar advances in treating canine diseases as well. To accomplish this, The Ohio State University college of Veterinary Medicine established a biospecimen repository or "tissue bank" to collect samples from dogs affected by these diseases so that the genetics and molecular biology can be more closely studied.
The Biospecimen Repository collects samples of tumors and normal tissue from dogs and cats, and stores these tissues under controlled conditions for future use by multiple investigators. The banking effort at The Ohio State University was selected by the Canine Comparative Oncology Genomics Consortium (CCOGC) as one of three veterinary institutions nationwide to begin populating a multi-institutional Tissue Bank. This National Cancer Institute-sponsored endeavor emphasizes the importance of comparative oncology research.
The Biospecimen Repository at The Ohio State University follows the guidelines established by the CCOGC for several specific types of tumors and similar established protocols for other tumors. Tissues are collected and archived only after receiving consent from the owners. This repository has been providing samples to researchers at OSU and Nationwide Children's Hospital resulting in the identification of new targets for therapy in osteosarcoma, melanoma, and lymphoma common to both humans and canines. As a result, these efforts have generated several new research opportunities that will benefit human and animal patients.
The Biospecimen Repository represents a remarkable resource that will assist investigators as they strive to develop new prevention and treatment strategies for both animals and people with a variety of illnesses.
|Collection & Processing||Tissue Request||Goals and Benefits|
|Explains how tissue is harvested, then processed to be store in the tissue bank.||What is the importance of the Biospecimen Repository?|