
Thomas J. Rosol, DVM, PhD
Diplomate ACVP
Professor, Veterinary Biosciences
Senior Advisor, Life Sciences,
University Office of Technology Commercialization and
Knowledge Transfer
Special Assistant to the Vice President for Research
The Ohio State University
307 Goss Lab
1925 Coffey Road
Columbus, Ohio 43210
Phone: (614) 292-5661
Fax: (614) 292-3544
rosol [dot] 1 [at] osu [dot] edu
Education and Speciality Training
- Diplomate, American College of Veterinary Pathologists-Anatomic Pathology, 1987
- PhD, Ohio State University, Veterinary Pathobiology, 1986
- DVM, University of Illinois (Valedictorian, 1st of 86 students), 1981
- BS, University of Illinois, Agricultural Science (highest honors), 1978
Expertise
- Thomas J. Rosol, DVM, PhD served as the Senior
Associate and Interim Senior Vice President for Research (2002-2005) and Dean
of the College of Veterinary Medicine (2005-2008) at The Ohio State University. Rosol currently serves a
Senior Advisor, Life Sciences for the OSU Office of Technology
Commercialization and Knowledge Transfer and Special Assistant to the
Senior Vice President for Research. Rosol is a Professor of Veterinary
Pathobiology in the Department of Veterinary Biosciences in the OSU College of
Veterinary Medicine.
- Dr. Rosol maintains an active, NIH-funded
research laboratory that uses molecular, in vitro, and in vivo techniques to
investigate the pathogenesis of human and animal cancers. Specifically, the
laboratory develops mouse models of cancer to study the pathogenesis of bone
metastasis, cancer-associated hypercalcemia, and human HTLV-1-induced T-cell
lymphoma. The molecular regulation of parathyroid hormone-related protein is
studied in vitro and in vivo using animal models of prostate, lung, and breast
cancer, and lymphoma. Breast and prostate cancer both metastasize to bone in humans,
but breast cancer typically induces osteolytic disease and prostate cancer
typically induces osteoblastic metastases. The Rosol laboratory has developed
mouse models of human cancer that mimic metastases in humans and are used to
investigate the pathogenesis and treatment of metastasis. New laboratory
expertise has been developed for in vivo imaging of cancer in mouse models
using bioluminescence, high resolution ultrasound, microCT, and near infrared
imaging of molecular markers. The lab is also examining the ability of
nanoparticles to enhance the ultrasound imaging of cancer molecular markers.